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Key research papers:

  • Oleari R, Caramello A, Campinoti S, Lettieri A, Ioannou E, Paganoni A, Fantin A, Cariboni A, Ruhrberg C. PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons. Development. 2019 Nov 5;146(21).
  • Plein A, Fantin A, Denti L, Pollard JW, Ruhrberg C. Erythro-myeloid progenitors contribute endothelial cells to blood vessels. Nature. 2018 Oct;562(7726):223-228.
  • Fantin A, Lampropoulou A, Senatore V, Brash JT, Prahst C, Lange C, Liyanage SE, Raimondi C, Bainbridge J, Augustin HG, Ruhrberg C. VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation. J Exp Med. 2017 Apr 3;214(4):1049-1064.
  • Raimondi C, Calleja V, Ferro R, Fantin A, Riley AM, Potter BV, Brennan CH, Maffucci T, Larijani B, Falasca M. A Small Molecule Inhibitor of PDK1/PLCĪ³1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion. Sci Rep. 2016 May 20;6:26142.
  • Liyanage SE, Fantin A, Villacampa P, Lange CA, Denti L, Cristante E, Smith AJ, Ali RR, Luhmann UF, Bainbridge JW, Ruhrberg C. Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization. ATVB. 2016 Jan;36(1):19-24.
  • Fantin A, Vieira JM, Plein A, Denti L, Fruttiger M, Pollard J, Ruhrberg C. NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Blood. 2013 Mar;121(12):2352-62. 
  • Fantin A, Vieira JM, Gestri G, Denti L, Schwarz Q, Prykhozhij S, Peri F, Wilson SW, Ruhrberg C. Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood. 2010 Aug;116(5):829-40.
Key review/protocol papers:

  • Brash JT, Ruhrberg C, Fantin A. Evaluating Vascular Hyperpermeability-Inducing Agents in the Skin with the Miles Assay. J Vis Exp. 2018 Jun 19;(136). doi: 10.3791/57524.
  • Fantin A, Ruhrberg C. The embryonic mouse hindbrain and postnatal retina as in vivo models to study angiogenesis. VEGF Signalling: Methods and Protocols (book chapter). Methods Mol Biol. 2015;1332:177-88.
  • Tata M, Ruhrberg C, Fantin A. Vascularisation of the central nervous system. Mech Dev. 2015 Nov;138 Pt 1:26-36.
  • Fantin A, Vieira JM, Plein A, Maden CH, Ruhrberg C. The embryonic mouse hindbrain as a qualitative and quantitative model to study the molecular and cellular mechanisms of angiogenesis. Nature Protocols. 2013 Jan;8(2):418-429.